Name | PEPLOMYCIN |
Synonyms | Peplocin PEPLOMYCIN Pepleocine NK-631{PEP Pepleomycin PEP-Bleomycin Bleomycin PEP |
CAS | 68247-85-8 |
EINECS | 269-484-0 |
Molecular Formula | C61H88N18O21S2 |
Molar Mass | 1473.59 |
Density | 1.0908 (rough estimate) |
Storage Condition | -20°C |
Refractive Index | 1.6700 (estimate) |
Physical and Chemical Properties | Pertomycin sulfate (Peplomycin Sulfate):C61H88N18O21 S2?H2SO4. [70384-29-1]. Light yellow amorphous powder, melting point 196-198 ℃. It's hygroscopic. Unstable to natural light. Soluble in water, methanol, acetic acid, dimethyl sulfoxide or dimethylformamide, slightly soluble in dioxane, insoluble in ethyl acetate, acetone, ether or benzene. In a sealed container, 37°C can be stable for 3 months, 50°C can be stable for 6 weeks, and room temperature can be stable for 30 months. [α] 43625-2.0 °(C = l, water). PKa 2.9,4.8,7.4,9.0. Acute toxic LD50 male rats, male mice, female mice (mg/kg):234,88,80 subcutaneous injection; 208,85,77 intraperitoneal injection; 245,51,45 intravenous injection. |